[(accessed on 1 February 2023)]
It works as a potent antioxidant, improves blood flow to nerves, and enhances glucose uptake all of which can help reduce burning, tingling, and pain associated with neuropathy.1 Clinical trials have shown consistent benefits at 600mg per day, particularly when taken long-term and under medical supervision.7 Benfotiamine (300mg per serving) Benfotiamine is a fat-soluble form of vitamin B1 (thiamine) with significantly better bioavailability than standard thiamine.46 It plays a central role in glucose metabolism and helps prevent the accumulation of harmful byproducts like advanced glycation end products (AGEs), which contribute to nerve damage in diabetes
It is also suitable for those looking to support methylation pathways, cognitive performance, and liver detoxification
Tumor-derived interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages
Glutathione depletion, pentose phosphate pathway activation, and hemolysis in erythrocytes protecting cancer cells from vitamin C-induced oxidative stress
It is important to note that the positive health impact of the MeD derives from the synergy of bioactive compounds and nutrients that interact with each other, producing increasing beneficial effects, which cannot be replicated by pharmacologically supplementing a single component [15, 62, 175, 190]