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Other Factors That May Increase Hemorrhoid Risk on Semaglutide Aside from bowel changes, semaglutide may contribute to hemorrhoid development in other ways: Reduced Food Intake Many people eat less when taking semaglutide

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Rapid weight loss without adequate protein leads to muscle loss, which slows metabolism and creates the "skinny fat" outcome where the scale looks good but body composition tells a disappointing story

Fatty foods require more time and digestive effort to process, and when combined with semaglutide's gastric-slowing effects, they may sit uncomfortably in the stomach for extended periods