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In vivo study Animals and experimental design All animal procedures were approved by the Ethics Committee of the Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, Egypt (Approval No.: PSAS-BSU-HAREC.025/08/08), and conducted in accordance with institutional, national, and international animal care guidelines

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A maintenance plan may include continued medication when appropriate, a lower or adjusted dose strategy, nutrition structure, strength training, periodic labs, waist measurement, weight trend monitoring, and follow-up visits

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The reduced TMAO levels observed in IBD likely reflect gut microbiota dysbiosis and altered host metabolism