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5-Amino-1MQ works through NNMT inhibition: not hormone mimicry, but modulation of cellular methylation and substrate handling

doi: 10.1128/AAC.01638-09 59 VitkoM.ValerioD

Its particularly effective at protecting against all sorts of toxic assaults on the body, particularly those absorbed through the gut: The stable gastric pentadecapeptide BPC 157 protects stomach cells, maintains gastric integrity against various noxious agents such as alcohol, nonsteroidal anti-inflammatory drugs (NSAIDs), and exerts cytoprotection/ adaptive cytoprotection/organoprotection in other epithelia, that is, skin, liver, pancreas, heart, and brain. (Park, et al, 2020)

10.1212/NXI.0000000000000423 Neurol

Intensively investigated cathelicidins are protegrins from swine, indolicidin from cattle, human LL-37, CAP 18 from rabbits, and CRAMP from mice [103, 105]