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Once in use, most can tolerate room temperature (up to 86F or 30C) for limited periods that vary by product: Wegovy (semaglutide): 28 days at room temperature Ozempic (semaglutide): 56 days at room temperature Zepbound/Mounjaro (tirzepatide): 21 days at room temperature Maintaining proper temperature during international travel is critical to preserve medication efficacy

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