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Several patterns emerge from this data

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ALOX15 KD normalized the intracellular GSH ( P = 0.003), while chemical inhibition of 15LO1 had a marginal, but insignificant effect ( P = 0.066)

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This review highlights GSH as a critical regulator of oxidative stress, inflammation, and immune function, with depletion potentially contributing to chronic inflammatory and cardiovascular diseases

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