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REDEFINE 1 -- CagriSema phase 3 (Aronne et al., 2025): CagriSema 2.4/2.4 mg produced 22.7% mean weight loss at 68 weeks vs 2.1% placebo

NTS acts as a relay station for incoming information to the central automatic network (CAN), which includes key areas such as the hypothalamic paraventricular nucleus, locus coeruleus, brachiocephalic nucleus, and limbic system

Published - July 24, 2026 03:40 pm IST

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Acquired GHD occurs due to injuries or damage to the hypothalamus or pituitary gland (e.g., via head trauma, infections, tumors, or treatments such as radiation therapy)

However, translating these technologies from laboratory settings to clinical practice remains a major hurdle