Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile
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Telomere dysfunction and reduced telomerase activity in oocytes are standard features of female subfertility and advanced maternal age [72]
The latter then donates an amino group to an alpha-keto acid, alpha-ketoglutarate, to form an amino acidpyridoxal 5-phosphate Schiffs base intermediate that is then reduced to form glutamate
Consistently, compounds like SFN are known to cause G2/M cell cycle arrest in various cancer cell lines, thereby suppressing tumor growth (113)
Pecot CV, Wu SY, Bellister S, Filant J, Rupaimoole R, Hisamatsu T, Bhattacharya R, Maharaj A, Azam S, Rodriguez-Aguayo C, Nagaraja AS, Morelli MP, Gharpure KM, Waugh TA, Gonzalez-Villasana V, Zand B, Dalton HJ, Kopetz S , Lopez-Berestein G, Ellis LM, Sood AK