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Where bacteriostatic water contains a bacteriostatic preservative to prevent microbial contamination over time, sterile water is free from preservatives and additives

However, if you have been advised to take higher doses of B12, you may need to take a separate B12 supplementfor example, if you need to address a deficiency

However, practical considerations may guide your choice

A randomized trial published in the European Journal of Pain found that vitamin B12 significantly improved pain scores in patients with chronic low back pain compared to placebo

Primary Handling Editor: Yanina-Yasmin Pesch, in collaboration with the Nature Metabolism team

Sterile water containing 0.9% benzyl alcohol, used as a research-grade solvent for reconstituting lyophilized peptides