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Efficacy endpoints for semaglutide compared to placebo, stratified by obesity class at baseline, were assessed using both the full analysis set (all randomized participants according to the intention-to-treat principle, regardless of treatment discontinuation) and the on-treatment data (including only patients receiving allocated study medication)

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Color differences may occur in the product due to natural ingredients

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Until such studies are conducted, the combination remains investigational and should be approached with appropriate caution, written informed consent, and consideration of FDA MedWatch reporting for any adverse events that occur with off-label combination use