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So, while it feels that the GLP-1 is not working, instead it could be inability to cope with difficult aspects of life without food that is impeding progress

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When kidney function declines, measured by estimated glomerular filtration rate (eGFR), medications may accumulate in your system longer than intended

Additionally, participants in the Bilge 2021 study reported mild side effects of restlessness, and some participants experienced generalized seizures even after cessation of treatment [78]

Sankowski AJ, Lebkowska UM, Cwikla J, Walecka I, Walecki J