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Participants who stopped semaglutide at week 68 (orange) regained most of their lost weight within a year net loss shrank from 17.3% to 5.6% by week 120

Semaglutide often has broader insurance acceptance and more affordable compounding options, making it the practical choice for long-term treatment

Ivanov, K

(2.2) To reduce the risk of sustained eGFR decline, end-stage kidney disease and cardiovascular death, increase the dosage to 1 mg once weekly after at least 4 weeks on the 0.5 mg dosage

doi: 10.1056/NEJMoa1605943

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