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Cytosolic GOT1 and mitochondrial GOT2, which together comprise the malate-aspartate shuttle, interconvert oxaloacetate and aspartate using glutamate or -KG as substrates 33

This is why direct-to-patient programs like TrimrX are often a more accessible option

Severe cases can have emergency signs like vomiting blood or dehydration

According to the mass of the sample, the GSH content of the sample was calculated by substituting the formula

doi:10.1056/NEJMoa1603825 Practice Committee of the American Society for Reproductive Medicine

Depending on your situation, your provider may order lab work or a physical exam to make sure we have the full picture before recommending a treatment