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The OsDHAR sequence was then manually built into the electron density map using the COOT program and restrained refinement was performed using the REFMAC5 program 32,33

For this reason, we typically recommend a short series of injections, often beginning with a package of three treatments or more, depending on the therapy and your individual health goals

This is covered at the assessment before any treatment is booked

Healthcare practitioners are encouraged to use clinical judgement with case-specific dosing based on intended goals, subject body weight, medical history, and concomitant medication and supplement usage

Generative AI statement The author(s) declare that no Generative AI was used in the creation of this manuscript

10.3389/fphar.2023.1230174 175 YangB.QiaoY.YanD.MengQ