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10.1126/scisignal.2005189 36 GuptaD.GuptaV.NathD.MiglaniC.MandalD.PalA

Body composition

doi: 10.1089/ars.2007.1716

Time of day Twice-daily dosing (most common): Morning: 30-60 minutes before breakfast Evening: 30-60 minutes before dinner OR before bed Consistent timing each day helps Once-daily dosing: Morning preferred (on empty stomach) Or before bed for healing during sleep Choose what fits your schedule Does timing matter much

however, this is only partial, as it dose-dependently reduced the number of flinches during phase 1 but did not decrease their number during phase 2

The REDEFINE trials showed the combination produces approximately 22.7% body weight reduction, significantly more than either peptide alone