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for the enrichment of certain ABR genes that are not detected in the baseline levels does not imply they are not present, but are, in fact, present at very low abundance levels that are simply below the level of detection 6

For instance, CRISPR/Cas9-mediated knockout of the YTHDF1 gene would provide a more definitive genetic loss-of-function model

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While high iodine intake usually leads to mild and short-term thyroid issues, it can trigger severe and potentially life-threatening hyperthyroidism in some individuals (46)