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Human and rat results should therefore be shown separately and should not be combined into one cross-species ranking

To further elucidate the therapeutic mechanisms underlying D-CuPs multivalent interactions, comprehensive proteomic analysis revealed two pivotal transcriptional regulators, the tumor suppressor protein p53 and histone deacetylase 7 (HDAC7) to be potential mechanistic targets

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DOI: 10.1038/s41467-017-01114-1 Formulation strategies for therapeutic peptide stability pH, ionic strength, co-solvency