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During the treatment, no significant change in the body weight of the mice was observed, indicating that NP4 has a high biocompatibility (Supplementary Fig

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In a third study, Julio Rosenstock, M.D., from the University of Texas Southwestern Medical Center in Dallas, and colleagues found that the mean HbA1c reductions were significantly greater with cagrilintide-semaglutide (2.4 mg each and 1.0 mg each: 2.33 and 2.10 percent, respectively) versus placebo (0.66 percent) at week 40 in 274 adults with type 2 diabetes using basal insulin

By way of non-limiting examples, the formulations are administered as otic drops, as intratympanic injections, as foams or as otic paints