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A landmark 2023 trial demonstrated that semaglutide reduced cardiovascular events by 20% in patients with obesity and existing heart disease, partly through improvements in blood pressure and weight loss

Ginger tea or chews, bland foods like crackers or broth-based soups, and cold or room-temperature meals often go down easier than hot ones

Trial data show an average increase of about 2.7 to 3.2 beats per minute in some studies, and real-world program data report a slightly higher proportion of people reporting increased heart rate on semaglutide versus not on it (for example, roughly 16 percent versus 11 percent after two years in an extensive registry analysis)