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Thyroid function also plays a role in metabolic response, and uncontrolled hypothyroidism may blunt weight loss effects

But apart from its action on insulin, GIP is also believed to improve the bodys long-term lipid storage, such that it reduces fat accumulation in the skeletal muscles and organs.14 This dual activity is likely what accounts for tirzepatides superlative efficacy for weight loss in clinical studies

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Today, weight loss medications have proven to be responsible for many people in the United States and around the world achieving their goals

A hypothetical 60 mg dose could overstimulate these pathways rather than enhance therapeutic effects

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