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It represents the shortest fully functional fragment of endogenous growth hormone-releasing hormone (GHRH)

For GLP-1 compounds metabolized through hepatic and renal pathways, this interaction may amplify side effects like nausea, vomiting, or gastrointestinal distress

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Upon its discovery, GLP-1 immediately sparked great interest among drug developers as it showed tremendous potential to be developed as a novel antidiabetic medication