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For Diabetes: Other medications such as SGLT2 inhibitors, DPP-4 inhibitors, metformin, or insulin Diabetes self-management education programs and lifestyle coaching For Weight Loss: Other weight-loss medications such as bupropion-naltrexone, phentermine-topiramate, and orlistat Bariatric surgery, especially for people with severe obesity or weight-related complications Natural GLP-1 boosters, such as: Eating meals high in fiber, protein, and healthy fats Limiting refined carbohydrates and sugar Getting enough sleep and regular physical activity Next Steps What Should You Do If You Think GLP-1s Might Be Right for You

The surge in adverse events may impact lawsuits alleging that GLP-1 drugmakers failed to warn users about serious gastrointestinal and metabolic risks adequately

In August, leading Republicans asked the Government Accountability Office to determine whether CMS premium stabilization program was legal

Endoscopic sleeve gastroplasty plus lifestyle intervention in patients with metabolic dysfunction-associated steatohepatitis: a multicenter, sham-controlled, randomized trial

Semaglutide is classified as a GLP-1 receptor agonist, a type of medication that mimics the effects of the glucagon-like peptide-1 hormone in the body

Knapp G, Hartung J