Andropause and somatopause Endocrinol Metab Clin North Am
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ER stress inhibits placental protein synthesis, eventually triggering apoptosis [234]
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With regard to Wnt/-catenin signaling, the electrophilic ,-unsaturated ketone moiety of 4-HNE reacts with the side chain of -catenin to form covalent adducts that alter the turnover of -catenin