Response: We appreciate the comments on the C-APC methodology
Research shows GHK-Cu's therapeutic dose is approximately 300-fold below its toxic threshold
Unlike GH itself, which has a very short half-life of approximately 3 to 4 minutes, IGF-1 circulates with a half-life of around 18 hours, making it a more stable and consistent measure of GH activity
10.3389/fonc.2018.00248 Summary Keywords apitherapy, anti-inflammation, anticancer, antimicrobial, neuroprotection, wound healing Citation Sadek KM, Shib NA, Taher ES, Rashed F, Shukry M, Atia GA, Taymour N, El-Nablaway M, Ibrahim AM, Ramadan MM, Abdelkader A, Abdo M, Imbrea I, Pet E, Ali LS and Abdeen A (2024) Harnessing the power of bee venom for therapeutic and regenerative medical applications: an updated review
doi: 10.1097/HJR.0b013e32828622d7
In addition, CJC-1295 can also be modified with the drug affinity complex (DAC), which improves the molecule's pharmacokinetics