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doi: 10.3390/nu14163265 [DOI] [PMC free article] [PubMed] [Google Scholar] 173

Clinical trials indicate bethanechol is no more effective than placebo, and its use is associated with significant dose-dependent unpleasant side effects including blurred vision, bradycardia, bronchospasm, and GI upset (Barrett 1981

Other mechanisms by which methylene blue may induce neuroprotective effects include facilitating the degradation and clearance of tau proteins, which is a characteristic feature of Alzheimers disease, promoting autophagy, and reducing amyloid plaque accumulation

Alcohol-associated PAGln production and cardiovascular dysfunction are transmissible traits To address the relative contribution of alcohol-induced gut microbial reorganization towards increased PAGln levels and subsequent cardiovascular dysfunction, we performed microbial transplantation of gut commensals from PF and AF mice into nave mice using a previously reported protocol with modifications as described (Fig

(No pass, no play!) PRO TIP: It is also worth noting that high doses of vitamin C (ascorbic acid) may destroy vitamin B12