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Patients were required to have exercise limitation and high symptom severity due to HFpEF reflected by a 6MWD of 100425 m and a KCCQ-CSS 80 at baseline, along with objective evidence of HF, as demonstrated by at least one of the following: (1) elevated NT-proBNP (200 pg ml 1 in sinus rhythm or 600 pg ml 1 in atrial fibrillation)
237 Multiple clinical trials have shown its potential in treating COVID-19 disease with admirable safety and tolerability
Patient Outcomes and Long-Term Benefits Patient-reported outcomes demonstrate enhanced daytime energy and reduced sleep fragmentation after several months on GLP-1 and sleep apnea therapy
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Mild Side Effects These side effects are reported anecdotally and tend to resolve on their own within a few days of use or dose adjustment: Headache or light-headedness Mild nausea or upset stomach (especially with oral use) Fatigue or lethargy in the first few days of use Appetite changes (increase or decrease) Injection site irritation redness, swelling, or tenderness Mild dizziness, nausea, and local irritation are among the most commonly reported side effects of subcutaneous BPC-157 injection, typically resolving within 2472 hours. Milekic, T
