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Since there have been some interesting developments in both the diagnosis and treatment of B12 deficiency, and since B12 deficiency remains so common, this seems like a good opportunity for some updates

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Eur J Neurol 23:958963 Martinez-Hervas S, Mendez M, Folgado J et al (2017) Altered Semmes-Weinstein monofilament test results are associated with oxidative stress markers in type 2 diabetic subjects

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Importantly, high levels of glutamate in the TME have been found to induce neutrophil transformation into an immunosuppressive state [175]

Shukla et al., 2018)