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These findings strongly suggest that G6PD deficiency in endothelial cells shifts the redox balance towards enhanced oxidative stress coupled with insufficient vasoprotection by NO

As biologics, these medications require strict temperature control throughout transportation and storage to maintain their efficacy

This bacterial shift can happen within weeks of sustained dry mouth and can persist even after saliva flow normalizes, because the new bacterial colonies have established themselves

Treatment Options for CCD Although theres no single medication that will help all dogs with Canine Cognitive Dysfunction, if your dog is diagnosed with CCD, there are several options available for treatment

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Tell your doctor about all your other medicines, especially: valproic acid or divalproex sodium (Depakene or Depakote) a diuretic or "water pill"