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In aging models using the mutant insulin-like receptor gene (daf-2, CF1041) and mammalian transcription factor family protein homologs (daf-16, CF1038), catalpol enhanced antioxidant gene expression and the antioxidant response, thus delaying aging by activating the insulin/IGF-1 signaling pathway in nematodes (Zhao et al., 2024

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EPITHALON WYKAZUJE DZIAANIE REGENERACYJNE I ANTYSTARZENIOWE DZIKI: Aktywacji telomerazy wydua telomery w komrkach, co chroni DNA przed degradacj i wspiera ich ywotno

Fukutomi T, Takagi K, Mizushima T, Ohuchi N, Yamamoto M

Effects of dexamethasone on fluoroquinolone-induced tendinopathy in rats To test the hypothesis derived from the human data, we developed a rat tendinopathy model by chronic oral administration of pefloxacin, and dexamethasone was co-administered (Figure 4A)