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We review various aspects of the relationship between ferroptosis and cancer, including the genetic basis, epigenetic modification, cancer stem cells, and the tumor microenvironment, to provide information and support for further research on ferroptosis

Conclusion In conclusion, this study reveals that excessive GSH intake may contribute to chemotherapy resistance in breast cancer patients, identifying high GSH intake as an independent risk factor for tumor recurrence

Orlando, G

The Plant Cell

PMID: 37277863 Adv Sci (Weinh) Addressing Clinical Limitations of Glutaminase Inhibitors: Novel Strategies for Osimertinib-Resistant Lung Cancer by Exploiting Glutamine Metabolic Dependency