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Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling

In hair follicles with reduced overall pigmentation, hair bulb melanocytes displayed variably reduced expression or absent ATM expression

2 for the 1-week dosing interval after a single dose and simulated at steady state

The delayed gastric emptying effect is primarily mediated through GLP-1 receptor activation and contributes to increased satiety and reduced caloric intake, which are beneficial for weight management

Nonsyndromic hearing impairment is associated with a mutation in DFNA5

They function by mimicking a natural gut hormone