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This review comprehensively summarizes literature and shows that, acupuncture, as an adjuvant therapy can play a potential important role in the treatment of PSCI by regulating the microbiota-gut-brain-axis

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For example, a patient with biopsyproven celiac disease who remains symptomatic despite strict gluten avoidance and has objective markers of increased permeability might eventually be a candidate for a regulated larazotidebased therapy, if and when such products are approved