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Tzankova, V., Gorinova, C., Kondeva-Burdina, M., Simeonova, R., Philipov, S., Konstantinov, S., Petrov, P., Galabov, D., Yoncheva, K., 2016

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In addition to the PERK-ATF4-CHOP axis, other key ER stress pathways, such as IRE1/XBP1 and ATF6 also contribute to the UPR, collectively managing protein misfolding and restoring homeostasis, or, if stress persists, trigger cell death (Tabas and Ron, 2011)

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