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Matsuzawa A, Ichijo H: Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

Such complexity, in a way, is expected from the complicated interaction between multiple genetic loci to influence the development of ASD phenotypes, which can be further confounded by the involvement of specific environment stressors [108]

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Although not documented in Keshan disease, it is possible that selenium deficiency may increase the virulence of viruses with the potential to invade and damage the heart muscle (57)

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Exposure to canonical ferroptosis inducers, including erastin, RSL3, and glutamate, triggers a rapid loss of mitochondrial membrane potential (m), thereby impairing oxidative phosphorylation and compromising respiratory ATP production [101, 102]