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Investigators found that, in intermediate age-related macular degeneration eyes, the area of hyperreflective foci along the retinal pigment epithelium was more predictive of disease progression than drusen volume or intraretinal hyperreflective foci, suggesting the area may serve as a harbinger of focal atrophy formation and may predict where hypertransmission defects form in these particular cases

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Ellingsgaard H, Hauselmann I, Schuler B, et al