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This is probably explained by the fact that S-adenosylmethionine (SAM), which is important for many epigenetic processes, is regenerated by methylcobalamin, whereas cyanocobalamin reduces it (as we explored above)

Fortified Plant-Based Foods : Many cereals, plant-based milks and nutritional yeast are enriched with synthetic B12, making them a practical alternative for those avoiding animal products

Conditions such as Crohns disease or Celiac disease can inflame the gut lining, making it difficult for the small intestine to absorb B12 efficiently

Research shows that 20% to 50% of these patients might not have enough B12

It can be found naturally in many food sources, however some people who do not get enough B12 end up developing a deficiency

They can sometimes cause B12 levels to be too high