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In many patients, it is a metabolic and cognitive risk amplifier

Center SA, Warner KL, Randolph JF, Sunvold GD, Vickers JR: Influence of dietary supplementation with (L)-carnitine on metabolic rate, fatty acid oxidation, body condition, and weight loss in overweight cats

McEwen et al., 2012)

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Patients report fewer injection-site reactions and simplified storage requirements compared to injectable preparations

The present mini-review therefore aims to summarize the contribution of ED to CVD in obesity and T2DM, to synthesize the pre-clinical and clinical evidence supporting endothelial and cardiovascular benefits of GLP-1RAs, and to delineate current controversies and research priorities that will inform future incretin-modulating interventions