Relative contraindications (metformin use, proton pump inhibitors) require monitoring
2011 Aug;28(8):1857-65
Abbreviations CM: Citrulline malate NO: Nitric oxide ATP: Adenosine triphosphate MAS: Malate aspartate shuttle MDH: Malate dehydrogenase NIRS: Near infrared spectroscopy PFK: Phosphofructokinase TCA: Tricarboxylic acid HR: Heart rate GI: Gastrointestinal GVT: German volume training VO 2peak : Peak oxygen consumption EMG: Electromyography References Agudelo LZ, Ferreira DM, Dadvar S, Cervenka I, Ketscher L, Izadi M, Ruas JL (2019) Skeletal muscle PGC-11 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance
At our clinic, the clearest clinical indicator for Sermorelin comes from patients on a weight loss protocol who are experiencing difficulty gaining or keeping muscle mass
Energy expenditure in acetaminophen-induced fulminant hepatic failure
If the safety and modest efficacy data from the published trials translate to our patient population, it would give us a tool that acts directly on fat cell metabolism rather than appetite, with a side effect profile that appears extremely well-tolerated
