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The broad spectrum of its therapeutic applications highlights the need for continued research and clinical trials to fully understand and harness its potential

refrigerate PEER-REVIEWED EVIDENCE Kraus D, Yang Q, Kong D, et al

Nicotine activates melanocyte activity and melanin production, with oral mucosa pigmentation frequency rising in a dose-response relationship with smoking [38]

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162 It enhances mitophagy by deacetylating mitochondrial proteins and activating the PINK1/Parkin pathway, thereby promoting mitochondrial quality control and supporting autophagy during glucocorticoid-induced muscle atrophy