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Additionally, tirzepatide may benefit atherosclerosis and lower the risk of major adverse cardiac events

Wound Healing, Skin Repair, and Regeneration Research A multicenter, randomized, evaluator-blinded, placebo-controlled study in diabetic neuropathic ulcers reported greater median plantar-ulcer closure with topical glycyl-L-histidyl-L-lysine copper gel compared with vehicle, 98.5% versus 60.8%, and lower ulcer infection incidence, 7% versus 34% [3]

1m creates a more concentrated mix (50mcg per IU), while 2m provides a more diluted solution (25mcg per IU), which is better for microdosing or sensitive users

Potential for weight regain during the transition

IV therapy can have more acute side effects during the infusion (flushing, etc.), but these are manageable with proper administration