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Using cellular models of PD (BV-2 microglia in mice and SH-SY5Y cells in humans), Caenorhabditis elegans , and Drosophila melanogaster , an LD reduced Mucuna pruriens seed extract was prepared and evaluated for its anti-PD effects

At 0.2mmol/l CuSO 4 , no significant differences were observed, but higher concentrations (0.41.4.2mmol/l) significantly increased toxicity in HepG2 ATP7B-KO cells (Fig

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