There is a boxed warning for thyroid C-cell tumors, based on rodent studies
GLP-1R is found in many organs like pancreas, kidney, GI tract and brain, but is highly expressed in pancreas
When providers use diagnosic codes for obesity, we will be better able to realize the rates of obesity
"Actions of Thiols, Persulfides, and Polysulfides as Free Radical Scavenging Antioxidants"
Additional Sources Larkin J, Chiarion-Sileni V, Gonzalez R, et al
Contact your GP or IBD team promptly if you experience any of the following whilst taking weight loss injections: Severe or persistent abdominal pain, particularly if different from your usual Crohn's symptoms Significant worsening of diarrhoea or new-onset bloody stools Persistent vomiting preventing adequate fluid or medication intake Signs of dehydration (dark urine, dizziness, reduced urination) Unexplained fever or signs of infection Severe constipation or inability to pass wind (potential obstruction) Symptoms suggesting pancreatitis (severe upper abdominal pain radiating to the back) stop the medication immediately and seek urgent medical attention For severe symptoms, contact NHS 111 for urgent advice or go to A&E/call 999 if you experience severe abdominal pain with vomiting, inability to pass stool or wind, or signs of severe dehydration