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This review summarizes the existing knowledge derived from animal studies on the effects of GLP-1RAs and GLP-1RA related peptide polyagonists on NAFLD in an attempt to illuminate areas of uncertainty and provide the groundwork for future animal and clinical research in the field

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Some patients carry genetic profiles that reduce their receptor sensitivity, meaning standard doses may not produce optimal appetite suppression

Emerging preclinical research has identified GLP-1 receptors in various immune cells and tissues, leading to scientific interest in potential anti-inflammatory properties