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MiRNAs play important regulatory roles in a variety of biological processes such as cell proliferation, intercellular signaling, cell growth, cell death, cellular differentiation, apoptosis, and cancer metabolism 76,77,78

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Similar to nonsilent immune forms of regulated necrosis, ferroptotic cell death can release damage-associated molecular patterns (DAMPs) that promote the development of multiple inflammatory diseases and trigger the innate immune system

Thereafter, RPMI 1640 containing 1% FBS was added to prevent proliferation