Research shows berberine treatment increases circulating GLP-1 levels in both animal and human studies, though the magnitude remains modest compared to pharmaceutical interventions
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Diabetes Technology & Therapeutics, 25(2), 117-126
Nature 372:425432 Banks WA, Kastin AJ, Huang W, Jaspan JB, Maness LM (1996) Leptin enters the brain by a saturable system independent of insulin
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Loo et al., 1991), and the 1993 description of a high charge state of the intrinsically disordered metal-free apo-metallothionein and lower charge states of the folded metallothionein-metal complexes (Yu et al., 1993) likely represents the first report on application of this technique to the analysis of IDPs