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Suppression of the production of corticotropin may lead to suppression of endogenous corticosteroids

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In the SURMOUNT-1 trial, 91% of participants on 15 mg lost at least 5% of their body weight, and 57% lost 20% or more

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ROS in the ovaries is mainly produced in the macrophages, leukocytes, and cytokines present in the follicular fluid