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The samples were cooled on ice for 5 min and were vortexed following the addition of 1 ml of 70% TCA

MOTS-C: A Mitochondrial-Derived Peptide MOTS-C is a small peptide (16 amino acids) that is notable for being encoded within the mitochondrial genome, rather than the nuclear genome like most peptides and proteins

Sample SJ, Hao Z, Wilson AP, Muir P

Unfortunately, the practical implementation of this approach proved challenging, as exemplified by the suboptimal cargo release efficiency observed in template-derived constructs (e.g., S2-DOX)

First, it significantly increases the total percentage of the active molecule that successfully enters systemic circulation