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Based on these observations, we designed peptides in which the individual hydrophobic residues were substituted with alanine

Whereas creatinine-based estimates of GFR are able to predict risks associated with declining kidney function when eGFR levels fall to 60 mL/min/1.73m2 or less, GFR estimates based on cystatin C level are predictive at approximately 85 mL/min/1.73m2

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No pharmaceutical company pursues this because the peptide can't be patented in most jurisdictions, eliminating profit incentive

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(The supernatant can be stored at -80 for 10 days.) Blood sample Plasma: Sample is centrifuged at 600 g and 4 for 10 minutes