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Additionally, the promoter features an antioxidant response element (ARE) and metal response element (MRE) within the first 160 bp of the transcription start point, which respond to oxidative stimuli such as H 2 O 2 and tert-butylhydroquinone [35]

It plays a vital role in regulating iron metabolism by chelating iron, thereby inhibiting microbial growth through iron deficiency and interacting with lipopolysaccharide (LPS) to develop bactericidal effects (Zarzosa-Moreno et al., 2020)

Research models by Bhm et al

The prevailing medical advice emphasises informed decision-making, individualised assessment, and appropriate monitoring rather than blanket approval or prohibition

The PPP is an alternative route of glucose metabolism, accounting for no more than 10% of glucose utilization [28]