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1016 CB-839, a BPTES derivative, has overcome these limitations and has received FDA approval

[DOI] [PubMed] [Google Scholar] 256.Bartolone R.S., Rao T.L

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This matters commercially because the same biological pathway can support multiple high-burden conditions that are often present in the same patient population

These changes are evident in BN, BED, FA, and ADHD (88, 99, 124, 125, 129, 148)